Cognitive reserve, lifestyles and dementia

 
   Lead Investigator:    Feifei Jia
   Institution      :    Shandong University
   E-Mail           :    jff@sdu.edu.cn
   Proposal ID      :    1350



   Proposal Description:
   lifestyle risk factors are associated with clinical dementia through vascular and neurodegenerative brain pathologies, it is possible that cognitive reserve(CR) may buffer the effect of unhealthy lifestyles on the clinical manifestation of dementia. However, the interaction between lifestyle factors and CR to dementia remains poorly understood. It is unclear whether individuals with low CR are more likely to benefit from healthy lifestyles or whether the low CR counteracts potential healthy lifestyles benefits. Therefore, we aimed to determine to what extent a favorable profile based on modifiable risk         factors relates to a lower risk of dementia among individuals at low, intermediate or high CR